Increased SNR efficiency in velocity selective arterial spin labeling using multiple velocity selective saturation modules (mm-VSASL)

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Velocity-selective arterial spin labeling.

In pathologies in which slow or collateral flow conditions may exist, conventional arterial spin labeling (ASL) methods that apply magnetic tags based on the location of arterial spins may not provide robust measures of cerebral blood flow (CBF), as the transit delay for the delivery of blood to target tissues may far exceed the relaxation time of the tag. Here we describe current methods for A...

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Velocity Selective Inversion Pulse Trains for Velocity Selective Arterial Spin Labeling

Introduction In velocity selective arterial spin labeling (VSASL) (1), blood is tagged based on flow velocity, without spatial selectivity. The most attractive feature of this tagging approach is that it is in principle immune to transit delay effects, and is therefore of potential utility in ischemic diseases such as stroke. A primary drawback of existing implementations of VSASL is that the t...

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Demonstration of velocity selective myocardial arterial spin labeling perfusion CMR

Background Arterial spin labeling of the heart has been shown to estimate myocardial perfusion and perfusion reserve at a single short-axis slice for coronary artery disease assessment. However, current spatial labeling methods suffer from transit delay effects when imaging is extended to more than a single slice. Velocity selective (VS) labeling is a promising alternative that does not suffer ...

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Intravascular effects in velocity-selective arterial spin labeling: the choice of transit delay and cutoff velocity

W-C. Wu, E. C. Wong fMRI Center, University of California, San Diego, La Jolla, CA, United States Introduction Velocity selective arterial spin labeling (VS-ASL) creates a modulation of longitudinal magnetization of blood on a basis of flow velocity (1,2) rather than spatial distribution as has been commonly used in conventional ASL methods. By incorporating a VS pulse train, only blood flowing...

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Velocity Selective Arterial Spin Labeling using an Adiabatic Hyperecho Pulse Train

E. C. Wong, M. Cronin UCSD, La Jolla, CA, United States Synopsis In Velocity Selective Arterial Spin Labeling (VS-ASL), arterial blood is magnetically tagged using velocity selective pulses with no spatial selectivity, resulting in small and uniform transit delays throughout the region of interest. We introduce here the use of a hyperecho based tagging pulse train that consists of BIR-4 adiabat...

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ژورنال

عنوان ژورنال: Magnetic Resonance in Medicine

سال: 2014

ISSN: 0740-3194

DOI: 10.1002/mrm.25462